Expanded Hemodialysis (HDx) is the next evolution in hemodialysis that brings us a step closer to the natural kidney
Conventional/large middle molecular (500-45,000 Da) uremic toxins have been linked to the development of inflammation, cardiovascular disease (CVD) and other dialysis related comorbidities1-3
CVD is strongly associated with inflammation, atherosclerosis and calcification. ~ 50% of patients with kidney failure (KF) die from CVD4-6
Traditional high-flux membranes, have limited capability to remove conventional and large middle molecular uremic toxins (up to 45,000 Da)7
The unique design of the Theranova membrane delivers superior removal of conventional/large middle molecules (up to 45,000 Da),1,8-10 compared to high-flux membranes, while selectively retaining essential proteins and maintaining stable albumin levels.8,11,12
HDx therapy showed a significant reduction in hospital days and in-center medication usage, in a retrospective analysis (n=81).13 A Randomized Control Trial (n=171) showed 43% reduction in all-cause hospitalizations.14 Improvement in certain inflammatory markers were observed in select patients (n=41).15
HDx therapy may improve patient reported kidney disease quality of life outcomes including symptom burden, restless leg syndrome (RLS) criteria uremic pruritus and dialysis recovery time. 8,10,16,17
Simply change the dialyzer membrane to expand clearance
and CHANGE EVERYTHING for your patients.
Watch the video to hear how one dialysis patient's experience with HDx therapy changed her life
See how HDx enabled by Theranova works
Watch the video for more information on Theranova's mechanism of action.
For single use only.
Rx Only. For safe and proper use of these devices refer to the Instructions for Use.